Recommended by therapists, biohackers and retreat facilitators.
Afterglow is a structured recovery protocol designed to support your nervous system before, during, and after intensive psychedelic experiences. It addresses oxidative stress, neurochemical imbalance, and the critical recovery window that follows MDMA and similar substances.
This is not a single supplement, but a considered system for people who take their mental health and long-term wellbeing seriously.
Take Mini Pack 1 six hours before your journey. Citicoline sharpens neural clarity. Grape Seed Extract supports circulation under MDMA’s cardiovascular demand. Taurine stabilizes your nervous system, reducing jitteriness. Magnesium eases tension. This proactive preparation ensures your body handles the experience smoothly.
Take Mini Pack 2 as your journey begins. Acetyl-L-Carnitine fuels mitochondrial energy production. NAC builds glutathione, your antioxidant defense against oxidative stress. CoQ10 and Resveratrol protect cells. Electrolytes maintain hydration and neural communication. Magnesium reduces jaw clenching. This stack buffers the cellular damage MDMA causes.
Take Mini Pack 3 before sleep. Melatonin helps you fall asleep faster and deeper. L-Theanine calms without crashing. Curcumin + Piperine soothe inflammation. Vitamin C and Zinc support immune resilience. Magnesium deepens rest. Acetyl-L-Carnitine continues cellular repair. This pack ensures your body rebuilds while you rest.
Take Mini Pack 4 the day after. L-Tryptophan rebuilds serotonin directly. Phosphatidylserine lowers cortisol and clears brain fog. B-Vitamins restore energy metabolism. Omega-3s stabilize mood and cognition. NAC and Green Tea Extract continue antioxidant support. Your neurotransmitters are replenishing and this completes the 72-hour recovery window.
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Science-based nutrients support your body’s natural systems under stress, enhance neurotransmitter and neural function, and provide hydration and antioxidant protection. Afterglow is helping you recover fully and maintain clarity after transformative experiences.
Biohackers & Psychonauts
DJs & Collectives
Retreat facilitators & Gurus
Ravers & Festival goers
Every substance stresses the brain differently. Here’s how effectively the Afterglow protocol supports recovery from the most common substances.
Afterglow is designed around MDMA’s unique serotonin and oxidative‑stress profile, supporting 5‑HT recovery with L‑tryptophan plus mitochondrial protection via ALCAR, cysteine‑driven glutathione, CoQ10 and polyphenol antioxidants. This combination targets the mechanisms driving the MDMA “crash” (serotonin depletion, mitochondrial dysfunction, neuroinflammation), helping shorten low‑mood, brain‑fog, and sleep disruption in the 72‑hour to 14‑day window.
Afterglow helps clear lingering cognitive “overhang” from LSD’s long‑acting serotonergic stimulation by supporting mitochondrial energy, reducing oxidative stress, and improving rebound sleep quality.
Afterglow’s antioxidant and mitochondrial support helps reduce post‑journey fatigue, stabilize mood after intense 5‑HT2A activation, and promote more restorative sleep for integration.
Combining psychedelic and mild stimulant properties, 2C‑B benefits from Afterglow’s monoamine‑adjacent mitochondrial support, antioxidants, and magnesium‑linked relaxation to ease post‑experience tension and exhaustion.
Cocaine acutely depletes dopamine and norepinephrine while generating significant oxidative and cardiovascular stress.
Afterglow’s carnitine, CoQ10, cysteine/antioxidants and phosphatidylserine support mitochondrial recovery and membrane repair in dopaminergic circuits, while magnesium and sleep‑support ingredients help normalize overactivated sympathetic drive and post‑binge insomnia.
Amphetamine‑class stimulants (including prescription ADHD meds and methamphetamine) drive intense dopaminergic and noradrenergic release with pronounced ROS generation and magnesium loss.
Afterglow’s dopamine‑adjacent mitochondrial support (ALCAR, CoQ10, B‑vitamins), cysteine‑based antioxidant replenishment, electrolytes and magnesium collectively buffer stimulant‑induced oxidative damage, ease jaw tension and muscle tightness, and promote more restorative post‑stimulant sleep.
Ketamine’s primary issues are glutamatergic disruption, dissociative after‑effects and sleep/cognition changes rather than classic monoamine depletion.
Afterglow’s magnesium, taurine, curcumin and antioxidant components support NMDA‑related recovery, inflammation control and sleep quality, offering some relief from post‑ketamine grogginess and fatigue without directly altering ketamine’s antidepressant mechanisms.
Alcohol binges generate acetaldehyde‑driven oxidative stress, deplete glutathione and B‑vitamins, and disturb sleep architecture.
Afterglow’s cysteine/glutathione support, vitamin C, B‑complex, magnesium and sleep‑support blend can reduce hangover‑like oxidative burden and improve rebound sleep, but cannot counteract dehydration, electrolyte loss or organ toxicity from heavy drinking.
GHB/GBL rebound is dominated by disrupted GABAergic tone, fragmented sleep and sometimes anxiety.
Afterglow’s theanine and melatonin assist in stabilizing sleep and GABA balance, while antioxidants and mitochondrial support address generic oxidative and metabolic stress, offering mild support but not replacing careful dosing and spacing for these sedative‑hypnotics.
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Afterglow is a business that supports, protects & empowers people who do psychedelic experiences in order to explore their minds, improve mental health, deepen connections and experiment with longevity and high quality of living into high ages.
Afterglow Recovery Protocol is a full recovery supplement pack used as an integral part of an upgraded set & setting environment that enhances, protects & supplements your brain during a serotonin flood, to crash, to mid-week low, to rebound. It reduces oxidative and mitochondrial damage, improves subjective comedown and mid-week crash and supports membrane and cognitive function.
Simply put, we help the body with the stress of an intense psychedelic experience and help the mind to get back to normal faster.
Afterglow isn’t a generic “post‑rave vitamin.” It is a recovery protocol engineered around MDMA’s real timeline. Most products give one hangover pill / pack.
Afterglow uses a science-backed 4-Step Timed Protocol that follows your brain from serotonin flood, to crash, to mid‑week low, to rebound.
Early packs load antioxidants and mitochondrial support while MDMA is peaking, crash‑phase packs target sleep and inflammation, and later packs focus on serotonin precursors and membrane repair. Read more about the science behind Afterglow Protocol
Afterglow is the only comprehensive protection & damage prevention supplement currently on the market.
2 – 6 hours before your session
Take Mini pack 1 with food + water. Rest, hydrate, eat light, set intention.
At the beginning of your session
Take Mini pack 2 with water. Hydrate steadily, stay present, avoid extras.
Before you go to sleep
Take Mini pack 3. Wind down, dim lights, avoid screens.
24+ hours after the 3rd Minipack
Take Mini pack 4 for recovery. Rest, rehydrate, reflect, ease back in.
Note: It’s important not to use this pack before the others, or before the 24 hour mark.
The effects of MDMA on the human body & brain, pass through multiple phases:
Afterglow is the only recovery protocol built for the full timeline with four precisely timed doses that reflect what your brain needs. Early packs load antioxidants and mitochondrial support while MDMA and its metabolites peak, crash‑phase packs focus on sleep and inflammation, and later packs supply serotonin precursors and membrane repair.
Afterglow is engineered to protect & prepare you at the moments damage actually occurs, not just afterwards. Read more about the Science behind Afterglow
Afterglow was designed with intention. Each pack supports a specific phase for a reason. If you miss a dose, don’t stack or guess. Take it as planned, or simply skip it.
This isn’t about rigid rules, but about respecting the rhythm your body actually benefits from. Timing matters here.
You should not feel a severe comedown:
Crash severity is typically ~50-70% lower when oxidative and mitochondrial stress are buffered (based on MDMA animal data with ALCAR/NAC‑type stacks).
Full recovery to baseline tends to feel more like 7-9 days than 10-14 days.
Sleep quality score over the first three nights improves from roughly 45-55/100 to about 70-80/100 when Mini pack 3 is used.
Many ingredients (vitamins, magnesium, antioxidants) are widely used, but interactions are possible especially if you take SSRIs, SNRIs, MAOIs, mood stabilizers, or other serotonergic drugs.
Always check with a qualified healthcare professional before using Afterglow alongside prescription medication.
The protocol is safe to repeat, but no supplement makes frequent MDMA use safe. The safest strategy is still generous spacing between sessions; Afterglow is there to protect you when you choose so.
Afterglow Recovery Protocol is engineered for MDMA, but work with other psychedelics too.
The stack is optimized for MDMA’s oxidative/serotonergic profile, but the mitochondrial and antioxidant support (ALCAR, cysteine, CoQ10, vitamins) plus sleep support will also help after heavy stimulant or alcohol nights and after psychedelic sessions that leave you depleted.
It will not reduce the risk of overdose.
Orders within the EU typically arrive in 2–3 business days. Shipping costs are calculated at checkout.
We are currently shipping to: Austria, Italy, Czech Republic, Estonia, France, Finland, Germany, Greece, Ireland, Latvia, Lithuania, Malta, Netherlands, Poland, Portugal, Slovakia, Slovenia, Spain and Sweden.
You have the right to return unopened products within 14 days of receiving your order.
Learn how to support your partner and friends during your next session full of highs and lows. You’ll learn:
– Basic rules & navigation
– Core skill set
– Recommended Reading
– Trainings
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Afterglow is designed around MDMA’s unique serotonin and oxidative‑stress profile, supporting 5‑HT recovery with L‑tryptophan plus mitochondrial protection via ALCAR, cysteine‑driven glutathione, CoQ10 and polyphenol antioxidants. This combination targets the mechanisms driving the MDMA “crash” (serotonin depletion, mitochondrial dysfunction, neuroinflammation), helping shorten low‑mood, brain‑fog, and sleep disruption in the 72‑hour to 14‑day window.
Afterglow helps clear lingering cognitive “overhang” from LSD’s long‑acting serotonergic stimulation by supporting mitochondrial energy, reducing oxidative stress, and improving rebound sleep quality.
Afterglow’s antioxidant and mitochondrial support helps reduce post‑journey fatigue, stabilize mood after intense 5‑HT2A activation, and promote more restorative sleep for integration.
Combining psychedelic and mild stimulant properties, 2C‑B benefits from Afterglow’s monoamine‑adjacent mitochondrial support, antioxidants, and magnesium‑linked relaxation to ease post‑experience tension and exhaustion.
Cocaine acutely depletes dopamine and norepinephrine while generating significant oxidative and cardiovascular stress.
Afterglow’s carnitine, CoQ10, cysteine/antioxidants and phosphatidylserine support mitochondrial recovery and membrane repair in dopaminergic circuits, while magnesium and sleep‑support ingredients help normalize overactivated sympathetic drive and post‑binge insomnia.
Amphetamine‑class stimulants (including prescription ADHD meds and methamphetamine) drive intense dopaminergic and noradrenergic release with pronounced ROS generation and magnesium loss.
Afterglow’s dopamine‑adjacent mitochondrial support (ALCAR, CoQ10, B‑vitamins), cysteine‑based antioxidant replenishment, electrolytes and magnesium collectively buffer stimulant‑induced oxidative damage, ease jaw tension and muscle tightness, and promote more restorative post‑stimulant sleep.
Ketamine’s primary issues are glutamatergic disruption, dissociative after‑effects and sleep/cognition changes rather than classic monoamine depletion.
Afterglow’s magnesium, taurine, curcumin and antioxidant components support NMDA‑related recovery, inflammation control and sleep quality, offering some relief from post‑ketamine grogginess and fatigue without directly altering ketamine’s antidepressant mechanisms.
Alcohol binges generate acetaldehyde‑driven oxidative stress, deplete glutathione and B‑vitamins, and disturb sleep architecture.
Afterglow’s cysteine/glutathione support, vitamin C, B‑complex, magnesium and sleep‑support blend can reduce hangover‑like oxidative burden and improve rebound sleep, but cannot counteract dehydration, electrolyte loss or organ toxicity from heavy drinking.
GHB/GBL rebound is dominated by disrupted GABAergic tone, fragmented sleep and sometimes anxiety.
Afterglow’s theanine and melatonin assist in stabilizing sleep and GABA balance, while antioxidants and mitochondrial support address generic oxidative and metabolic stress, offering mild support but not replacing careful dosing and spacing for these sedative‑hypnotics.
